Clinical Research

Pushing the Boundaries of Medical Innovation

At CLS Health, we are dedicated to the advancement of medicine. We believe that clinical research is essential to improve people’s health and well-being. For over 12 years, our physicians have partnered in clinical research trials to provide our patients with cutting-edge treatment options. Our clinical research trials are designed to precisely test the safety and efficacy of new treatments. With a commitment to patient-centered care, these clinical research studies occur within the comfort of the practice office. Additionally, all clinical trials are managed and executed in partnership with Tranquil Clinical Research—an esteemed clinical research organization that is dedicated to patient wellness and ethical values. Together we strive to bring new treatments to our patients that can improve health outcomes.

Participants undergo careful screening to ensure the most appropriate patient is enrolled in the study. Screening consists of a review of information, such as age, previous treatments, and other medical conditions.

Eligible participants meet with one of our highly trained research staff to review the study and answer any and all questions. Our research staff’s number one job is to ensure the rights, safety, and wellness of our participants are protected and maintained throughout your participation in the study. Informed consent is a document that has been approved by an independent review board (IRB) and is reviewed and signed by each participant prior to the conduct of any study procedures.

Participation in a clinical trial incurs no cost for anything conducted specifically for the study. The study sponsor may also offer compensation for time and travel. Information regarding risks, benefits, responsibilities, compensation, the reason for the study, and more will be discussed during the informed consent review.

Study participation is voluntary. Participants may withdraw from study participation at any time. The decision to withdraw will not result in any penalty nor adversely affect your relationship with your study doctor or practitioner.

Open Studies
Ways to Schedule an Appointment

Open Studies

Hypothyroidism Study

Researching Treatments for Hypothyroidism Care

Do you suffer from Hypothyroidism? Researchers are studying an investigational product to assess its effects on thyroid hormone levels and quality of life.

Qualifications:

  • Are between 18 and 75 years old
  • Have been diagnosed with primary hypothyroidism
  • Have been on continuous thyroid replacement therapy with levothyroxine for at least 12 months

Requirements:

You will receive study treatment.

There will be 12 visits with your doctor.

You will be compensated for your time for study visits and laboratory sample collections.

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call  713-907-6054 or view our brochure

There will be compensation for your time.

Lung Bio Study

Have you been diagnosed with Pulmonary Hypertension due to COPD?

Qualifications:

  • Be 18 years of age or older
  • Must have an established diagnosis of chronic obstructive pulmonary disease (COPD) with suspected or confirmed pulmonary hypertension
  • Must be able to walk at least 100 meters during a 6-minute walk test without limitations in mobility using no oxygen or oxygen at no more than 10 liters per minute
  • Willing and able to use Sponsor provided devices (actigraph, spirometer, and smart device)

Requirements:

  • Willing to undergo Right Heart Catheterization
  • Inhaled Treprostinil for PH-COPD

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call 713-907-6054

There will be compensation for your time.

Click here for more information regarding this study or call 713-907-6054

Lung Bio PERFECT Study Information

FSGS Study

FSGS is a type of kidney disease that occurs when scar tissue develops on the parts of your kidneys that act as filters (the glomeruli). The scar tissue makes it more difficult for the filters to do their job. Instead of keeping essential proteins in your body, the injured filters allow these proteins to flow into the urine. This can lead to high levels of protein in your urine, a condition called proteinuria. Podocytes are cells lining the kidney that, in their normal state, prevent proteinuria. Injury to, and loss of, podocytes is a central component of FSGS. Protecting podocytes from further injury, and stopping proteinuria, may help slow the progression of kidney disease and potentially prevent kidney failure.

What is the purpose of this trial?

Currently, there is no approved therapy in the US to treat Focal Segmental Glomerulosclerosis (FSGS). Advances in drug therapy are key to treating FSGS in its early stages and preventing further kidney damage. The TRACTION-2 Trial is testing an investigational medication (GFB-887) that has the potential to reduce the amount of protein in urine and preserve kidney function in patients with kidney disease. If you have FSGS, this trial may be an option for you.

Qualifications:

  • Are 18 to 75 years of age
  • Have been diagnosed or are being treated for FSGS
  • Have high levels of protein in your urine (proteinuria)

Requirements:

Diagnosis based on documented biopsy or genetic testing and currently receiving ACE inhibitor or ARB for 3 months.

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call 713-907-6054

There will be compensation for your time.

Click here for more information regarding this study or call 713-907-6054

FSGS Study Information

Overactive Bladder Study

Diagnosed with OAB? Participate in a clinical study for a new wearable OAB device.

Qualifications:

  • Be 18 years of age or older
  • Diagnosed with Overactive Bladder
  • Have an average of 11 urinary frequency events per day
  • Have daily access to WiFi

Requirements:

Wearing an investigational device for 30 minutes 1 to 3 times per week in your home.

12-week study period

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call 713-907-6054

There will be compensation for your time.

Click here for more information regarding this study or call 713-907-6054

Over Active Bladder Clinical Study Information

Pediatric Varicella Vaccine Study

This study looks at different strengths of a potential new investigational vaccine against chickenpox (varicella). The study will look at how safe the study vaccine is and will also determine whether it works to help prevent chickenpox in children.

Why is this study important?

Chickenpox is a very contagious infection that can cause serious complications in children. Access to several chickenpox vaccines is important because vaccination is the only way to help protect children from chickenpox.

Qualifications:

  • Your child may be able to take part if they:
  • Are 12-15 months of age
  • Are in good health
  • Have received the first 3 doses (primary series) of a pneumococcal conjugate vaccine, a vaccine against infections caused by the Streptococcus pneumoniae bacteria, which cause ear, lung, and other infections.

Requirements:

If your child takes part, they will be in this study for about 6 months. Your child will need to:

Complete 3 study visits and 2 phone contacts for safety follow-up.

Receive the study vaccine or reference vaccine and 3 other approved vaccines that are part of routine vaccination schedules:

M-M-R II against measles, mumps, and rubella

Havrix against hepatitis A infection

Prevnar 13, a pneumococcal conjugate vaccine, against infections caused by the Streptococcus pneumoniae bacteria, which cause ear, lung, and other infections

Have 1 blood sample collected about 6 weeks after vaccination.

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call 713-907-6054

There will be compensation for your time.

Systemic Lupus Erythematosus Study

Systemic Lupus Erythematosus (SLE), also known as “lupus,” is an autoimmune disease that affects multiple organ systems and is unpredictable in disease severity, with periods of illness or flares alternating with periods of remission. The presentation of lupus can affect many different parts of the body but frequently involves the joints, skin, kidneys, blood cells, and mucus membranes (the lining of the mouth, nose, throat, stomach, and intestines) which can result in symptoms such swollen joints, rash, foamy urine, changes in red or white blood cells, and oral ulcers, among others. Disease prevalence is approximately 1 in 1,000 individuals overall but varies with race and ethnicity.

What is the purpose of this trial?

Most therapies used to treat SLE are only partially effective and have considerable toxicity. The purpose of the study is to investigate if the investigational product, BIIB059, can reduce disease activity and inflammation in people with active SLE compared to a placebo. BIIB059 is a type of antibody that has been developed to target certain cells that are thought to play a role in the development of lupus. It is hoped the study drug can improve symptoms in people with SLE.

Qualifications:

  • Participants must be at least 18 years of age
  • Have been diagnosed with moderate-to-severe SLE for at least 6 months
  • Are currently taking SLE medication

Requirements:

You will receive an investigational product via injections under the skin every month.

Visits will last about a year and a half and include around 22 visits to the study site.

Contact us NOW! Space is limited.

Tranquil Clinical Research

Call 713-907-6054 or view our brochure

All study-related care and study medication are at no charge.

Ways to Schedule an Appointment